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        當前位置:首頁 >產品中心>細胞庫>人正常細胞>CRL-1573293 人胚腎細胞

        293 人胚腎細胞

        簡要描述:CRL-1573 293 人胚腎細胞,ATCC 細胞|細胞系|細胞株|腫瘤細胞|細胞|貼壁細胞|懸浮細胞|。細胞庫管理規(guī)范,提供的細胞株背景清楚,提供參考文獻和培養(yǎng)條件

        • 產品型號:CRL-1573
        • 廠商性質:生產廠家
        • 更新時間:2025-07-08
        • 訪  問  量:2246

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        詳細介紹

        CRL-1573 293 人胚腎細胞


        Designations:293

        Depositors:FL Graham

        Biosafety Level:2 [Cells contain adenovirus ]

        Shipped:frozen

        Medium & Serum:See Propagation

        Growth Properties:adherent

        Organism:Homo sapiens

        Morphology:CRL-1573 293 人胚腎細胞


        Source:Organ: embryonic kidney

        Permits/Forms:In addition to the MTA mentioned above, other ATCC and/or regulatory permits may be required for the transfer of this ATCC material. Anyone purchasing ATCC material is ultimay responsible for obtaining the permits. Please click here for information regarding the specific requirements for shipment to your location.
        Restrictions:These cells are distributed for research purposes only. 293 cells, their products, or their derivatives may not be distributed to third parties.

        Applications:efficacy testing

        transfection host

        viruscide testing



        Receptors:vitronectin, expressed

        Tumorigenic:YES

        DNA Profile (STR):Amelogenin: X

        CSF1PO: 11,12

        D13S317: 12,14

        D16S539: 9,13

        D5S818: 8,9

        D7S820: 11,12

        THO1: 7,9.3

        TPOX: 11

        vWA: 16,19



        Cytogenetic Analysis:This is a hypotriploid human cell line. The modal chromosome number was 64, occurring in 30% of cells. The rate of cells with higher ploidies was 4.2 %. The der(1)t(1;15) (q42;q13), der(19)t(3;19) (q12;q13), der(12)t(8;12) (q22;p13), and four other marker chromosomes were common to most cells. Five other markers occurred in some cells only. The marker der(1) and M8 (or Xq+) were often paired. There were four copies of N17 and N22. Noticeably in addition to three copies of X chromosomes, there were paired Xq+, and a single Xp+ in most cells.

        Age:fetus

        Comments:Although an earlier report suggested that the cells contained Adenovirus 5 DNA from both the right and left ends of the viral genome [RF32764], it is now clear that only left end sequences are present.

        The line is excellent for titrating human adenoviruses.

        The cells express an unusual cell surface receptor for vitronectin composed of the integrin beta-1 subunit and the vitronectin receptor alpha-v subunit.

        The Ad5 insert was cloned and sequenced, and it was determined that a colinear seqment from nts 1 to 4344 is integrated into chromosome 19 (19q13.2).



        P37C.

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